Success rates of IVF depend upon many factors like
The age of the patient,
Number of IVF attempts
Cause and duration of infertility,
The eggs- their number, quality and maturity,
The sperms – their count, motility, and morphology,
Number of embryos and their quality,
And endometrial lining.
So for the success of IVF, a healthy egg with a viable sperm is required along with the uterus that is able to maintain the pregnancy. The age of the patient is a very important factor while considering the IVF success rates because the rate of fertility begins to decline from mid to late thirties of women.
The variables affecting a program's IVF success rates are:
1. The quality of the laboratory environment
2. The skill and experience of the embryology staff
3. The skill and experience of the reproductive endocrinologist doctor (fertility specialist)
4. The average number of embryos transferred per procedure
5. The cases taken on by the program for IVF treatment. There are "good" patients and "bad" patients in the sense that some couples are more likely than others to have success from IVF because of egg quantity and quality, female age, or other issues. Individuals who've failed in other programs, are over 38 years old, have borderline FSH values, have prolonged unexplained infertility, or are low responders have less chances of success as compared to individuals with good number of eggs, younger age, normal sperm parameters, and good endometrial lining.
Success rates depend on how you define success and calculate the total population.
1. Chemical pregnancy- The hCG levels more than 10 IU after 15 days of embryo transfer are considered positive for pregnancy, but not all cases have gestational sac or foetal node on ultrasound after 15 days
2. Clinical pregnancy- Gestational sac is there but foetal heart beat is not seen on ultrasound
3. Ongoing pregnancy rate- foetal heart beat seen by ultrasound
4. Live birth rate
The denominator in this calculation also affects the calculation of success rate. The denominator may be
1. The number of couples entering treatment
2. Or those going to oocyte retrieval
3. Or those having pre-embryos replaced into the uterus
Why Our Success Are Rates So High?
The ultimate goal is to help couples to conceive.
We individualize the treatment according to patient’s history
Have highly skilled team
Strict quality control
Use of the latest technologies
Commitment to ongoing learning